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Serotonin and Eyes

Serotonin and Eyes. Serotonin and problems with eyes have been found to be correlated in the pathological reasons involved in some of the eye conditions.



Serotonin (5-HT) is a biogenic monoamine that is synthesized from hydroxylation of tryptophan. It acts by three ways that is through dissemination, metabolism, and reuptake in synaptic cleft through specific systems of the membrane. Serotonin has been found to be involved in the pathogenesis of an eye condition called Glaucoma. Serotonin is basically an indolamine which is the precursor of melatonin and actually melatonin has been associated in decreasing the intraocular pressure in the eyes. This is the prime reason that melatonin could be used in glaucomatous therapy. Melatonin has also been found to have an inhibitory effect on the nitric oxide levels, thus this effect could also contribute towards protecting the cells from nitrosative stress.

Serotonin and its metabolites have been studied in glaucomatous optic neuropathy condition and these studies may form an important basis in looking at newer ways to treat Glaucoma.

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